• Site-specific cleavage of ribosomal RNA in Escherichia coli-based cell-free protein synthesis systems 

      Failmezger, Jurek; Nitschel, Robert; Kraml, Michael; Siemann-Herzberg, Martin; Sánchez-Kopper, Andrés (PLoS ONE, 2016)
      Cell-free protein synthesis, which mimics the biological protein production system, allows rapid expression of proteins without the need to maintain a viable cell. Nevertheless, cellfree protein expression relies on ...
    • Synthesis, properties, and two-dimensional adsorption characteristics of 5-amino[6]hexahelicene 

      Van der Meijden, Maarten W.; Gelens, Edith; Murillo-Quirós, Natalia; Fuhr, Javier D.; Gayone, Esteban; Ascolani, Hugo; Wurst, Klaus; Lingenfelder, Magalí; Kellogg, Richard M. (Willy, 2016)
      A convergent synthesis of racemic 5-amino[6]hexahelicene is described. Cross-coupling reactions are used to assemble a pentacyclic framework, and a metal-catalyzed ring-closure comprises the final step. The enantiomers ...
    • The release of wastewater contaminants in the Arctic: A case study from Cambridge Bay, Nunavut, Canada 

      Chaves-Barquero, Luis G.; Luong, Kim Hoang; Mundy, C.; Knapp, Charles W.; Hanson, Mark L.; Wong, Charles S. (Scopus, 2016)
      The treatment of municipal wastewater in the Arctic is challenging due to a variety of financial, operational, climatic and technical issues. To better understand the efficacy of current wastewater treatment in this ...
    • Towards a fuzzy logic model for chemical risk assessment by inhalation in laboratories 

      Obando, Óscar; Garita-Rodríguez, César (Proceedings of the 2015 IEEE 35th Central American and Panama Convention, CONCAPAN 2015, 2015)
      This paper presents a computational Fuzzy Logic Model for chemical hazards risk assessment by inhalation in laboratories. Some influence factors on chemical risk are deterministic but not completely measurable. As a ...
    • Tracking dipeptides at work-uptake and intracellular fate in CHO culture 

      Sánchez-Kopper, Andres; Becker, Max; Pfizenmaier, Jennifer; Kessler, Christian; Karau, Andreas; Takors, Ralf (AMB Express, 2016)
      Market demands for monoclonal antibodies (mAbs) are steadily increasing worldwide. As a result, production processes using Chinese hamster ovary cells (CHO) are in the focus of ongoing intensification studies for maximizing ...